Primitive Neuroectodermal Tumor of the Kidney
نویسندگان
چکیده مقاله:
Primitive neuroectodermal tumor (PENETs) is an uncommon malignancy of bone and soft tissue witch rarely occurs in the kidney. In more than 90% of the cases, the tumor cells relieves a balanced translocation (11; 22) (q24; q12). Immunohistochemical staining may be required for diagnosis of PENET. The cells of tumor express CD99, vimentin, NSE, FL1 but do not express Ck, LCA, myogenin, and WT1. We present a 36-year –old female with left –side tender abdominal swelling, and history of trauma to abdominal. CT imaging confirmed a huge solid mass of kidney, also extending into renal pelvis. Histological section of the lesion showed a malignant proliferation of small round cells in rosette-like pattern with foci of necrosis area. Tumor cells expressed high level of CD 99 antigen. The diagnosis of the lesion was primitive neuroectodermal tumors (PNET). Following-up after 6 months showed no recurrence.
منابع مشابه
primitive neuroectodermal tumor of the kidney
primitive neuroectodermal tumor (penets) is an uncommon malignancy of bone and soft tissue witch rarely occurs in the kidney. in more than 90% of the cases, the tumor cells relieves a balanced translocation (11; 22) (q24; q12). immunohistochemical staining may be required for diagnosis of penet. the cells of tumor express cd99, vimentin, nse, fl1 but do not express ck, lca, myogenin, and wt1. w...
متن کاملPeripheral Primitive Neuroectodermal Tumor of the Pelvis
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متن کاملperipheral primitive neuroectodermal tumor of the pelvis
the primitive neuroectodermal tumor (pnet) belongs to a group of highly malignant tumors and is composed of small round cells of a neuroectodermal origin. categorized in the same tumor family as ewing sarcoma, the pnet is most likely to occur in bones and soft tissues. however, a small number of pnet cases arising in the pelvis have been reported as well. we present three cases of pelvic pnet: ...
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عنوان ژورنال
دوره 8 شماره 2
صفحات 123- 126
تاریخ انتشار 2013-04-01
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